U.S. Pharmaceutical Excipients Market - Databook 2025 to 2034

The U.S. Pharmaceutical Excipients market size was estimated at USD 2.75 billion in 2024 and is projected to be worth around USD 4.93 billion by 2034, growing at a CAGR of 6.01% from 2025 to 2034.

Highlights of the U.S. Pharmaceutical Excipients Market

• By functionality, the binders & fillers segment dominated the U.S. pharmaceutical excipients market in 2024.
• By functionality, the coating agents segment shows lucrative growth during the forecast period.
• By excipient type, the lactose-based segment dominated the U.S. pharmaceutical excipients market in 2024.
• By excipient type, the cellulose-based segment shows notable growth in the forecast period.

Industry Valuation and Growth Rate Projection

The pharmaceutical excipients market involves the production and distribution of numerous substances used in drugs, nutraceuticals, and cosmeceuticals to improve availability for absorption, stability of therapeutics, and patient acceptability. Excipients come in a variety of forms, including fillers, disintegrants, binders, preservatives, carriers, and coating agents, guaranteeing the efficient delivery and absorption of active pharmaceutical ingredients (APIs). The United States Food and Drug Administration (FDA) plays a vital role in regulating excipients by meeting safety requirements and quality standards. Policies also aim to enhance FDA oversight of excipient supply chains, which include managing and inspecting producers both domestically and internationally to ensure said quality.

Market Trends

The increasing demand for natural and plant-based excipients. As users are demanding the increasing use of natural ingredients in their medication due to the association of these substances with lower side effects, the popularity of sustainable and eco-friendly products is rising, as more pharmaceutical firms are exploring natural excipients as opposed to synthetic excipients. This is not only useful for tackling environmental issues but also provides potential advantages in terms of biocompatibility and lowered side effects.

Restraint

Increasing backlash against synthetic ingredients and their possible side effects has led to consumer resistance against certain synthetic excipients, leading to higher costs as more funds are diverted into the research and development of these natural excipient-containing drugs.

Opportunities

The rising requirement for generic medicines is boosting the demand for versatile and cost-effective excipients. As patents for branded drugs expire and healthcare systems globally seek to decrease the costs of treatment, the market for generic drugs is proliferating, creating the latest opportunities for excipient producers. This is expected to lead to a rise in the demand for pharmaceutical excipients.

The advancement of multifunctional excipients can accomplish multiple roles in drug formulations, such as enhancing solubility, improving bioavailability, and managing drug release. These innovative excipients are becoming increasingly essential as drug formulations become more complex and customized medicine gains traction.

Recent Developments in the U.S. Pharmaceutical Excipients Market

• In February 2025, Eli Lilly and Company disclosed plans to bolster its domestic medicine production over therapeutic zones by building four new pharmaceutical producing sites in the United States.