U.S. Non-clinical Polymerase Chain Reaction (PCR) Market - Databook 2025 to 2034

The U.S. non-clinical polymerase chain reaction (PCR) market size was calculated at USD 4,048 million in 2024 and is predicted to attain around USD 5,742 million by 2034, expanding at a CAGR of 3.7% from 2025 to 2034.

Highlights of the U.S. Non-clinical Polymerase Chain Reaction (PCR) Market

• By application area, the basic research segment held a dominant presence in the market in 2024.
• By application area, the pharmaceutical research segment is expected to grow at the fastest rate in the market during the forecast period of 2025 to 2034.
• By product type, the reagents & consumables segment accounted for a considerable share of the market in 2024.
• By product type, the instrumentation segment is projected to experience the highest growth rate in the market between 2025 and 2034.
• By end-use, the pharmaceutical & biotechnology companies segment led the market.
• By end-use, the academic & research institutes segment is set to experience the fastest rate of market growth from 2025 to 2034.

Industry Valuation and Growth Rate Projection

The U.S. non-clinical polymerase chain reaction market for using PCR is on the rise due to the increasing use of PCR technologies. In the U.S., PCR is frequently used in agriculture, food safety, forensic sciences, and environmental monitoring. Farmers use PCR for detecting plant diseases and managing genetically modified organisms (GMOs), food processing companies use polymerase chain reaction to check for harmful bacteria including Salmonella and E. coli, U.S. forensic laboratories use PCR for investigating DNA in murder cases, and government and private laboratories use PCR to test for water and soil quality and air pollution. The U.S. is still the global leader in the development and implementation of non clinical PCR applications because of the solid research infrastructure in the U.S. and many high-tech laboratories using nonclinical PCR applications.

What are the Market Trends for the U.S. Non-clinical PCR Market?

• Forensic and law enforcement demand: PCR is being widely used in helping the U.S. police and crime labs in DNA analysis and supporting criminal investigations.
• Environmental Monitoring: PCR is used in tracking pollution in water, air, and land by government agencies and private labs.

What are the Market Restraints for the U.S. Non-clinical PCR Market?

• High equipment prices: PCR machines and kits are quite expensive, which makes it very difficult for small schools, labs, and food factories to implement and invest in such technologies.
• Need for skilled workers: PCR tests require skilled and trained staff to run the tests. The U.S. has a shortage of such professionals for running the PCR tests.
• Sample contamination risk: The PCR is very sensitive and can very easily be contaminated, even with the slightest mistakes, and lead to inaccurate results.

What are the Market Opportunities for the U.S. Non-clinical PCR Market?

• Food safety demand: PCR tests are being used to test for E. coli, Salmonella, GMOs, and allergens in the U.S. to follow the strict FDA and USDA rules.
• Growth in forensics: PCR technologies are being increasingly used in U.S. forensic labs for DNA profiling, which helps in investigations.
• STEM education expansion: Schools and colleges are adding PCR to their labs, thus introducing a new market in academic institutions.

What are the Recent Developments in the U.S. Non-clinical PCR Market?

• In September 2024, the Centers for Disease Control and Prevention (CDC) awarded the National Wastewater Surveillance System (NWSS), Multi-Pathogen Assay Development Optimization, Validation and Support contract to GT Molecular Inc.

U.S. Non-clinical Polymerase Chain Reaction (PCR) Market Companies:

• Thermo Fisher Scientific Inc.
• Promega Corporation
• QIAGEN N.V.
• Bio-Rad Laboratories Inc.
• Agilent Technologies Inc.
• BioMérieux S.A.
• Danaher Corporation
• Standard BioTools Inc.
• Takara Bio Inc.
• Eppendorf AG

U.S. Non-clinical Polymerase Chain Reaction (PCR) Market Market Segmentation:

By Application Area

• Basic Research
  
  • Gene Expression Analysis
  • Genotyping
  • Cloning & Mutagenesis
  • Methylation Analysis
  • Others 
• Applied Research
  
  • Agricultural Genomics
  • Environmental Testing
  • Others 
• Pharmaceutical Research
  
  • Drug Discovery & Development
  • Pharmacogenomics
  • Biomarker Identification
  • Others

By Product Type

• Instrumentation
  
  • Thermal Cyclers
  • Real-Time PCR Systems
  • Digital PCR Systems
• Assays and Kits
  
  • Gene Expression Assays
  • Genotyping Assays
  • Mutation Detection Kits
  • DNA/RNA Extraction Kits
• Reagents & Consumables
  
  • Enzymes 
  • Nucleotides
  • Primers & Probes
  • Buffers and Master Mixes
• Software & Services
  
  • Analytical Software for Data Interpretation
  • Custom Assay Design Services
  • Maintenance & Technical Support

By End-Use

• Academic & Research Institutions
• Pharmaceutical & Biotechnology Companies
• Government and Regulatory Laboratories
• Contract Research Organizations (CROs)